Animal study

Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs

He L, Feng D, Guo H, et al. Frontiers in Pharmacology 2022;13:1026182.

What it found

Intact BPC-157 had a half-life of under 30 minutes. About 14-19% of an intramuscular dose reached the blood in rats and 45-51% in dogs. It was broken down into small fragments and amino acids and cleared in urine and bile.

Limitations

Rats and dogs only. How it behaves in people has not been measured.

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