Preclinical safety evaluation of body protective compound-157, a potential drug for treating various wounds
Xu C, Sun L, Ren F, et al. Regulatory Toxicology and Pharmacology 2020;114:104665.
What it found
Single doses caused no treatment-related effects in mice, rats, rabbits or dogs. Repeated dosing was well tolerated in dogs apart from a reversible drop in creatinine at 2 mg/kg. No damage to genes or to developing fetuses was found.
Limitations
Animals only, so it does not establish safety in people. Run by the group developing the peptide in China.
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