Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission
Volkova A, Shadrina M, Kolomin T, et al. Frontiers in Pharmacology 2016;7:31.
What it found
Of 84 nerve-signalling genes in the frontal cortex, 45 changed expression 1 hour after Selank or GABA and 22 after 3 hours, with similar patterns for both. The authors suggest Selank may modulate the GABA system indirectly.
Limitations
Rats only. Gene activity, not behaviour or symptoms. From the Institute of Molecular Genetics, Moscow.
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