Open-label trial

Optimization of the treatment of anxiety disorders with selank

Medvedev VE, Tereshchenko ON, Kost NV, et al. Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova 2015;115:33-40.

What it found

30 patients received phenazepam alone and 40 received phenazepam plus Selank. The combination was reported to speed up improvement on a depression and anxiety scale and to reduce phenazepam side effects such as memory and attention problems, sedation and sexual problems, with better quality of life.

Limitations

Article in Russian. Unequal groups; the abstract does not describe randomisation, blinding or a placebo. Co-authored by researchers from the Institute of Molecular Genetics, where Selank research is concentrated.

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