The efficacy of semax in the treatment of patients at different stages of ischemic stroke
Gusev EI, Martynov MY, Kostenko EV, et al. Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova 2018;118:61-68.
What it found
Patients were split into early and late rehabilitation groups, each with and without Semax. Those given Semax had faster-rising and higher blood BDNF levels and better final scores on the Barthel daily-living index; the effect on weakness was smaller.
Limitations
Article in Russian. The abstract does not describe random allocation, blinding or a placebo, so it is listed here as open-label. BDNF in blood is a marker, not a functional outcome in itself.
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