Once-Weekly Semaglutide in Adults with Overweight or Obesity
Wilding JPH, Batterham RL, Calanna S, et al. New England Journal of Medicine 2021;384:989-1002.
What it found
Mean body weight change of -14.9% with semaglutide vs -2.4% with placebo. 86.4% vs 31.5% lost at least 5% of body weight.
Limitations
Adults without diabetes; both groups also had lifestyle intervention. Results after stopping treatment were not part of this trial.
Research and education only. Not medical advice. Many peptides on this site are not approved by the FDA for human use. Doses shown are the ones used in published studies and are not a recommendation. Talk to a licensed clinician before using any of them. Read the full disclaimer.