Randomised controlled trial

Metabolic Effects of a Growth Hormone-Releasing Factor in Patients with HIV

Falutz J, Allas S, Blot K, et al. New England Journal of Medicine 2007;357:2359-2370.

What it found

Visceral fat fell and lipid levels improved compared with placebo. Glucose measures did not differ significantly between groups.

Limitations

Only people with HIV and abdominal fat accumulation. More withdrawals for side effects on tesamorelin than on placebo.

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