Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties
Araj SK, Brzezik J, Mądra-Gackowska K, et al. International Journal of Molecular Sciences 2025;26:2691.
What it found
Summarises 25 years of cell, animal and computer studies: effects on melatonin, interleukin-2, telomerase and several enzymes. Notes that it is unclear whether these are its only mechanisms and that chemical and structural studies are limited.
Limitations
Narrative review; the studies it summarises come mostly from one group.
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