Pineal-regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa
Khavinson V, Razumovsky M, Trofimova S, et al. Neuro Endocrinology Letters 2002;23:365-368.
What it found
In rats with inherited retinal degeneration, epitalon was followed by better retinal electrical activity and structure. In patients with degenerative retinal disease, the authors reported a positive clinical effect in 90% of cases.
Limitations
PubMed indexes it as a controlled trial, but the abstract gives no patient numbers, control details or outcome measures. Single group; not independently replicated.
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