In vitro

Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity

Al-Dulaimi S, Thomas R, Matta S, et al. Biogerontology 2025;26:178.

What it found

An independent UK group. Epitalon lengthened telomeres in normal cells by raising telomerase. In two breast cancer cell lines it also lengthened telomeres, mainly through a different route (ALT, alternative lengthening of telomeres).

Limitations

Cell lines only. The finding that telomeres also lengthened in cancer cells is relevant to safety. A correction to the paper was published in November 2025.

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