The effect of topical tripeptide-copper complex on healing of ischemic open wounds
Canapp SO Jr, Farese JP, Schultz GS, et al. Veterinary Surgery 2003;32:515-523.
What it found
By day 13, wound area had fallen by 64.5% with GHK-Cu gel, 45.6% with vehicle gel and 28.2% with no treatment. Treated wounds had lower TNF-alpha, MMP-2 and MMP-9.
Limitations
Rats, eight per group. Topical gel on an ischemic skin-flap model. The product was made by the developer, ProCyte.
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