Randomised controlled trial

A prospective randomized evaluator-blinded trial of two potential wound healing agents for the treatment of venous stasis ulcers

Bishop JB, Phillips LG, Mustoe TA, et al. Journal of Vascular Surgery 1992;16:251-257.

What it found

Silver sulfadiazine 1% cream reduced ulcer size more than placebo. The tripeptide copper cream did no better than placebo.

Limitations

The abstract describes the product only as a biologically active tripeptide copper complex and does not name it as GHK-Cu. Topical use only. Negative result for the copper cream.

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