Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice
Mills KF, Yoshida S, Stein LR, et al. Cell Metabolism 2016;24:795-806.
What it found
Precursor study (NMN). In normal mice over a year of ageing, NMN was quickly converted to NAD+ in tissues and was followed by less weight gain, better energy metabolism, physical activity, insulin sensitivity, blood lipids and eye function, with no obvious toxicity.
Limitations
Mice only. Mouse ageing results often do not carry over to people.
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