Randomised controlled trial

Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials

Kingsberg SA, Clayton AH, Portman D, et al. Obstetrics & Gynecology 2019;134:899-908.

What it found

Sexual desire improved and related distress fell compared with placebo in both trials. Nausea was the most common side effect.

Limitations

Premenopausal women with acquired HSDD only. Critics have described the absolute size of the benefit as modest.

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