Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice
Siegel MP, Kruse SE, Percival JM, et al. Aging Cell 2013;12:763-771.
What it found
One hour after a single injection, muscle energy production in old mice rose to levels seen in young mice, with no effect in young mice. Old muscle was more fatigue resistant, and 8 days of treatment improved whole-body endurance.
Limitations
Mice only, short duration.
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