Effects of Elamipretide on Left Ventricular Function in Patients With Heart Failure With Reduced Ejection Fraction: The PROGRESS-HF Phase 2 Trial
Butler J, Khan MS, Anker SD, et al. Journal of Cardiac Failure 2020;26:429-437.
What it found
No improvement in heart volume or ejection fraction on MRI compared with placebo. Drug-related adverse event rates were similar across groups.
Limitations
Short (4 weeks) and small, so a longer-term effect cannot be ruled out, but the trial was negative.
Research and education only. Not medical advice. Many peptides on this site are not approved by the FDA for human use. Doses shown are the ones used in published studies and are not a recommendation. Talk to a licensed clinician before using any of them. Read the full disclaimer.