Growth hormone secretagogue

Ipamorelin (10 mg vial) dosage protocol

Dosage chart, U-100 syringe units and supplies for a 10 mg vial of Ipamorelin mixed with 3 mL. For the full research summary, see the Ipamorelin page.

01

Ipamorelin quick reference (10 mg vial)

Vial contents
10 mg Ipamorelin
Final volume
3 mL
Concentration
3.33 mg/mL
One U-100 unit
33.3 mcg in 0.01 mL
02

Ipamorelin dosage chart

Amounts as reported for this peptide, with the syringe measure for this vial. Reported use is not evidence that a schedule works or is safe, and none of this is medical advice.

Gradual, once daily (often at bedtime)

  • Subcutaneous injection, once a day
  • Community-reported

Reported in the research community. It has not been tested as a schedule in human trials. Worked out with a 10 mg vial + 3 mL bacteriostatic water (3.33 mg/mL, 33.3 mcg per unit).

Amounts as reported, with the syringe or spray measure for the vial below. Not a recommendation.
PeriodAmount each timeU-100 unitsVolume
Weeks 1-2100 mcg30.03 mL
Weeks 3-4150 mcg4.50.05 mL
Weeks 5-8200 mcg60.06 mL
Week 9 on250 mcg7.50.08 mL

Reconstitution steps

  1. Draw 3 mL of bacteriostatic water with a sterile syringe.
  2. Inject it slowly down the inside wall of the vial, not onto the powder, to avoid foaming.
  3. Swirl or roll the vial gently until the powder dissolves. Do not shake it.
  4. Label it with the date and the volume of water, and refrigerate at 2-8 °C (36-46 °F), away from light.
03

Supplies needed

Minimum supplies for each length of the schedule above, with 10 mg vials and 3 mL of water per vial. One new syringe per injection (two if over 1 mL), two alcohol swabs per injection, 10 mL water bottles.

Gradual, once daily (often at bedtime)

  • Subcutaneous injection, once a day
  • Community-reported
Minimum supplies, worked out from the amounts above. Add a margin for losses.
Item8 weeks12 weeks16 weeks
Injections5684112
Total peptide9.1 mg16.1 mg23.1 mg
Ipamorelin vials (10 mg)123
Bacteriostatic water3 mL6 mL9 mL
Water bottles (10 mL)111
U-100 insulin syringes5684112
Alcohol swabs (boxes of 100)112 (2)168 (2)224 (3)

Research supplier

For laboratory research use only.

Codex Research LabShips from Panama City · US domestic shipping

04

Peptide reconstitution

Try other volumes of water: the concentration and the units per amount change with it.

Reconstitution calculator

Arithmetic only. It assumes the vial holds exactly what the label says.

Concentration
3,333 mcg/mL
Per U-100 unit
33.33 mcg
Volume for your amount
—
Concentration of a 10 mg vial after adding the liquid, and peptide per U-100 unit (0.01 mL).
Liquid addedConcentrationPer unit
1 mL10,000 mcg/mL100 mcg
2 mL5,000 mcg/mL50 mcg
3 mL3,333 mcg/mL33.3 mcg
05

Ipamorelin vial and research context

  • Reconstitute: add 3 mL of bacteriostatic water for a 3.33 mg/mL solution.
  • Amounts in the chart: 100 mcg-250 mcg each time, by subcutaneous injection, once a day.
  • Easy measuring: at 3.33 mg/mL, one unit (0.01 mL) on a U-100 insulin syringe holds about 33.3 mcg.
  • Storage: freeze-dried, keep it sealed, cold and away from light (frozen for long storage). Once mixed, refrigerate at 2-8 °C and avoid freezing and thawing.

Ipamorelin is a synthetic five-amino-acid peptide that triggers growth hormone release by acting on the ghrelin receptor. It reached phase 2 trials for gut recovery after bowel surgery but is not FDA-approved for any use.

06

Ipamorelin 10 mg protocol overview

  • Primary calculation: 10 mg made up to 3 mL equals 3.33 mg/mL.
  • Amounts shown: 100 mcg-250 mcg per administration. Reported in the research community. It has not been tested as a schedule in human trials.
  • Route and frequency: subcutaneous injection, once a day.
  • Evidence ceiling: 2 of the 10 studies with a dose in our library were done in people.
  • Regulatory status: Not FDA-approved for any use. WADA: Prohibited at all times (growth hormone secretagogues).
07

How to read the Ipamorelin dosage chart

A 10 mg vial holds 10,000 mcg of Ipamorelin. Adding 3 mL gives 3.33 mg/mL, so one U-100 unit (0.01 mL) holds 33.3 mcg. To get the units for an amount, divide it by 33.3 mcg. The units are a volume mark on the syringe, not a measure of potency.

  • 100 mcg: 0.03 mL, or 3 U-100 units.
  • 150 mcg: 0.05 mL, or 4.5 U-100 units.
  • 200 mcg: 0.06 mL, or 6 U-100 units.
  • 250 mcg: 0.08 mL, or 7.5 U-100 units.

Vial coverage by mass: 100 full amounts of 100 mcg, 66 full amounts of 150 mcg, 50 full amounts of 200 mcg, 40 full amounts of 250 mcg per vial, before any handling loss.

If a different volume of water is used, every unit figure changes: recalculate with the calculator above.

08

Human Ipamorelin dosage evidence

Two published human studies exist. Neither looked at body composition, muscle, sleep or ageing, which are the uses often claimed online:

  • Healthy volunteers: healthy men received a single 15-minute intravenous infusion at one of five dose levels (8 men per level). Each dose produced one pulse of growth hormone that peaked at about 40 minutes and then faded; ipamorelin itself had a half-life of about 2 hours (Gobburu 1999).
  • Bowel surgery: in a double-blind phase 2 trial, 114 adults recovering from bowel resection received intravenous ipamorelin or placebo twice daily for up to 7 days. Time to tolerating a solid meal was 25.3 hours with ipamorelin and 32.6 hours with placebo, a difference that was not statistically significant. Side effect rates were similar in both groups (Beck 2014).

In short: ipamorelin has been given to people only briefly, by vein, in controlled settings. We could not find any published controlled trial of it given under the skin over weeks or months, so its effects and safety with longer use are unknown.

Doses used in human studies

  • Gobburu JV 1999: 4.21, 14.02, 42.13, 84.27 or 140.45 nmol/kg over 15 minutes (single dose; 8 men per dose level) (Intravenous infusion over 15 minutes; Single dose)
  • Beck DE 2014: 0.03 mg/kg twice daily, from postoperative day 1 to day 7 or hospital discharge (Intravenous infusion, twice daily; Up to 7 days)

Every study dose, including animal and cell studies, is in the Ipamorelin dose table.

09

Ipamorelin safety, side effects and evidence limits

Published human safety data cover single intravenous doses in healthy men and up to 7 days of intravenous use in hospital, where side effects were similar to placebo (Beck 2014). Nothing is known from controlled studies about repeated injections under the skin over months.

  • Product quality: ipamorelin sold online is not checked by any regulator. Doping control labs have found unexpected variants in black market products, including a modified form with an extra amino acid (Gly-ipamorelin) (Krug 2018).
  • Growth hormone effects: raising growth hormone over the long term can affect blood sugar, fluid balance and cell growth. These effects have not been studied for ipamorelin specifically.
  • Animal selectivity is not human proof: the "no cortisol rise" finding comes from pigs.
  • Injection risks: any injected product that is not sterile can cause infection or abscesses.
  • Sport: growth hormone secretagogues are on the WADA prohibited list at all times.
  • FDA: Not FDA-approved for any use.
  • WADA: Prohibited at all times (growth hormone secretagogues).
  • Evidence limits: reported use is not evidence that a schedule works or is safe. Animal doses do not convert to people, and research products are not made or checked for use in people.
  • Status checked on: Oct 26, 2026.
10

Questions about the Ipamorelin 10 mg vial

How much bacteriostatic water goes into a 10 mg Ipamorelin vial?

There is no single correct volume: it only changes the concentration. For a 10 mg vial, 1 mL gives 10,000 mcg/mL, 2 mL gives 5,000 mcg/mL, 3 mL gives 3,333 mcg/mL. More water makes small amounts easier to measure; less water keeps volumes small. Whatever volume is used, write it on the label.

What does one unit on an insulin syringe mean?

On a U-100 syringe, 100 units = 1 mL, so one unit is 0.01 mL. How much peptide that holds depends on the concentration of the vial, which depends on how much water was added.

Can doses from animal studies of Ipamorelin be converted to people?

No. Animal doses are reported per kilogram for a different species, and scaling them to people is not reliable. That is why Upzo shows each study dose next to its study, unconverted.

Research and education only. Not medical advice. Many peptides on this site are not approved by the FDA for human use. Doses shown are the ones used in published studies and are not a recommendation. Talk to a licensed clinician before using any of them. Read the full disclaimer.