Dosage chart, U-100 syringe units and supplies for a 10 mg vial of MOTS-c mixed with 3 mL. For the full research summary, see the MOTS-c page.
Amounts as reported for this peptide, with the syringe measure for this vial. Reported use is not evidence that a schedule works or is safe, and none of this is medical advice.
| Period | Amount each time | U-100 units | Volume |
|---|---|---|---|
| Weeks 1-2 | 200 mcg | 6 | 0.06 mL |
| Weeks 3-4 | 400 mcg | 12 | 0.12 mL |
| Weeks 5-6 | 600 mcg | 18 | 0.18 mL |
| Weeks 7-8 | 800 mcg | 24 | 0.24 mL |
| Week 9 on | 1 mg | 30 | 0.3 mL |
Minimum supplies for each length of the schedule above, with 10 mg vials and 3 mL of water per vial. One new syringe per injection (two if over 1 mL), two alcohol swabs per injection, 10 mL water bottles.
| Item | 8 weeks | 12 weeks | 16 weeks |
|---|---|---|---|
| Injections | 56 | 84 | 112 |
| Total peptide | 28 mg | 56 mg | 84 mg |
| MOTS-c vials (10 mg) | 3 | 6 | 9 |
| Bacteriostatic water | 9 mL | 18 mL | 27 mL |
| Water bottles (10 mL) | 1 | 2 | 3 |
| U-100 insulin syringes | 56 | 84 | 112 |
| Alcohol swabs (boxes of 100) | 112 (2) | 168 (2) | 224 (3) |
For laboratory research use only.
Codex Research LabShips from Panama City · US domestic shipping
Try other volumes of water: the concentration and the units per amount change with it.
Arithmetic only. It assumes the vial holds exactly what the label says.
| Liquid added | Concentration | Per unit |
|---|---|---|
| 1 mL | 10,000 mcg/mL | 100 mcg |
| 2 mL | 5,000 mcg/mL | 50 mcg |
| 3 mL | 3,333 mcg/mL | 33.3 mcg |
MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA, studied in cells and mice for effects on metabolism and exercise capacity. Human data only measure the body's own levels; it has not been tested as a medicine in published trials, and it is not FDA-approved.
A 10 mg vial holds 10,000 mcg of MOTS-c. Adding 3 mL gives 3.33 mg/mL, so one U-100 unit (0.01 mL) holds 33.3 mcg. To get the units for an amount, divide it by 33.3 mcg. The units are a volume mark on the syringe, not a measure of potency.
Vial coverage by mass: 50 full amounts of 200 mcg, 25 full amounts of 400 mcg, 16 full amounts of 600 mcg, 12 full amounts of 800 mcg, 10 full amounts of 1 mg per vial, before any handling loss.
If a different volume of water is used, every unit figure changes: recalculate with the calculator above.
No published trial has given MOTS-c to people. The human studies we found are observational: they measure the body's own MOTS-c.
These studies suggest MOTS-c is linked to metabolism and exercise in people, but they cannot show cause and effect, and they say nothing about what happens when someone injects it. There is no human evidence on its effects or safety as a supplement.
Every study dose, including animal and cell studies, is in the MOTS-c dose table.
Side effects and safety in people are unknown, because no published trial has given MOTS-c to humans. In its compounding review, FDA said products containing it may carry a risk of immune reactions and impurity problems, and that it had not identified any human exposure data.
There is no single correct volume: it only changes the concentration. For a 10 mg vial, 1 mL gives 10,000 mcg/mL, 2 mL gives 5,000 mcg/mL, 3 mL gives 3,333 mcg/mL. More water makes small amounts easier to measure; less water keeps volumes small. Whatever volume is used, write it on the label.
On a U-100 syringe, 100 units = 1 mL, so one unit is 0.01 mL. How much peptide that holds depends on the concentration of the vial, which depends on how much water was added.
No. Animal doses are reported per kilogram for a different species, and scaling them to people is not reliable. That is why Upzo shows each study dose next to its study, unconverted.
Research and education only. Not medical advice. Many peptides on this site are not approved by the FDA for human use. Doses shown are the ones used in published studies and are not a recommendation. Talk to a licensed clinician before using any of them. Read the full disclaimer.
